Autophagy is inhibited by ubiquitin ligase activity in the nervous system
Despite growing interest in the role of autophagy in neurons, it remains unclear how this process is regulated, in particular, how autophagy is spatially restricted in subcellular compartments in neurons.In click here this study, the authors use an unbiased proteomic approach to show that the autophagy initiating kinase UNC-51/ULK and autophagosome